Studies & Results of MTL-004: Rat Study Findings
MTL-004 Remains Detectable in the Rat Brain for 28 Days
Excess is excreted via urine & faeces
Intra-cranial MTL-004 paste delivered to the left brain remains
in-situ for ~28 days
78% of intra-cranial dose is excreted in 120 hrs (57% in urine) due to entry into circulatory system following rat microsurgery.
MTL-004 is Well-Tolerated Following Intra-Cranial Gel Dose in GBM
Body Weight Data for MTL-004, TMZ and Placebo Treated Rats after Tumour Resection
MTL-004 Administered in Gel at the Tumour Resection Site Demonstrates Superior Inhibition of GBM Recurrence
Tumour re-growth inhibited by MTL-004 following surgical removal of primary tumour in rats
MTL-004 has Demonstrated Excellent Improved Survival in GBM
Significantly Improved Probability of Survival of Treated Rats
(note: gender differences not statistically significant)
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